The NAD+ levels drop to 50% of our youth by middle age. Nicotinamide adenine dinucleotide (NAD+) is an essential molecule with crucial roles in over 400 metabolic reactions. We can maintain and boost healthy levels of NAD+ contributing to the below benefits by using nicotinamide adenine dinucleotide hydrogen (NADH): 1. Longevity 2. Mitigates Physiological Aging 3. Enhances Vascular Health and Circulation 4. Helps to repair DNA 5. Guards against Heart Disease 6. Supports Neurological Functioning 7. Upholds Metabolism 8. Improve Stem Cell Health 9. Enhances Muscular Strength 10. Regulates Body Fat

NADH supplement was shown safe without any side effect with up to 1200 mg per day for 6 weeks – 10 male and 2 female amateur runners between 27 and 50 years old, reported no obvious side effect. People who have used NADH supplements have not yet experienced any substantial negative side effects of taking NADH, which is a positive development.

The suggested dose for adults between the ages of 30 and 60, based on the results of effectiveness and safety studies in humans and animals, as well as calculations of optimal NADH doses, is 500 mg per day. People over the age of 65 can safely take 750 mg of NADH per day to get the most out of the supplement. NADH to Support Skin Health: Study indicated that 250–300 mg of NADH per day may help protect and heal sun-damaged skin. NADH to Improve Muscular Function: A study found that taking 250 mg of NADH daily for 12 weeks improves muscular function in males over 65. The same dosage for 10 weeks also showed an increment in insulin sensitivity and women’s muscles. NADH to Uphold Cardiovascular Health: Researchers are conducting a clinical trial to determine the effect of NADH on cardiovascular and metabolic health when given 250 mg daily. NADH to Support Fertility: A study demonstrated that a low dose of 350 mg per day in a 50 kg person NADH restored fertility, more than 1,400 mg per day did not demonstrate benefit, suggesting an appropriate human dosage is between 350 mg to 1,500 mg per day. NADH to Boost Metabolism: According to the results of scientific research , 1,000 mg of oral NADH supplement per day can enhance NAD+ metabolism in healthy middle-aged and older individuals. Renowned anti-aging genetic research Harvard professor Dr. David Sinclair has said in a recent interview that he himself takes powder form 1,000 mg of NADH daily in addition to 1,000 mg of resveratrol without seeing any harmful effects for over a decade. NADH's safety and efficacy are also being investigated in other clinical trials registered with the World Health Organization (WHO). There are no definitive studies demonstrating that NADH has adverse effects at regularly used levels (up to 1,000 mg per day), and the elevated NAM associated with such concentrations is unlikely to pose a substantial health concern. It is prudent to avoid doses of more than 1,000 mg per day if using oral capsules, as these dosages result in significant increases in NAM and may create methylation problems for certain individuals.

NADH is most effective when taken in the morning and can be ingested with water or food. NADH, boosting NAD+, has an impact on the circadian rhythm – the ingestion of NADH supplement should happen during the day and within six hours after being awake.

Consistently taking NADH supplements daily can yield observable results within two to three weeks. While physiological effects commence within the first fifteen minutes, tangible benefits, such as increased energy levels and heightened awareness, may become noticeable after the initial uses. Substantial changes in both internal and external aspects are anticipated to be more evident after a few weeks of regular use. Maintaining consistent dosage and frequency is crucial for optimal results, recognizing that individual responses may vary based on adherence to the supplement regimen.